What is the most important thing you could do to organize your life? Did you say get rid of the clutter? That's what I thought. "A Place for everything and everything in it's place," is good advice unless you have too many Things and not enough Places. Instead of going out and buying a bigger Place what do you say to just getting rid of some of the Things?
The problem is that for most of us, it's more difficult than it sounds. My preferred method is to start in one room. Box everything up that looks out of place, except for your kids maybe (or maybe not), and then toss it. If this sounds too difficult then you could have one of your friends do it for you and then you could do it for her at her house. I've never actually tried it but it sounds like a good plan doesn't it? Lighting a match to it would make it even more fun.
If you want a method that's a little less exciting, you could try my four-bin method. When I'm clearing out a room I use big cardboard boxes or Rubbermaid bins. If I'm clearing out a drawer or a small space I use plastic washtubs. Label your bins for take away (belongs in another room), give away, throw away, and put away.
Now set a timer and go for it. If it's not useful or beautiful then get rid of it. The less time you have to think about it, the less you will torture yourself. Don't make a big deal about the whole thing. Things are just things. They are not memories (take a picture) and they are not living beings (if they are, then use a really good disinfectant). Your life will not be ruined if you get rid of something that you might want later. Really. What's the worst that can happen? You might have to borrow it from a friend, you might have to buy a new one, or you might get organized!